Clinical Topic Summary Guidelines


Having a standardised approach to writing articles ensures that readers have a consistent experience and that the website, as a whole, feels cohesive. As a result, we’ve created some guidelines to assist you when writing your clinical topic summary.

If you are writing an article that covers several clinical conditions (e.g. an overview of dermatological emergencies) then review our multiple clinical topic overview guidelines to see how to structure this type of article.


Important points

  • Articles should provide a succinct overview of the relevant topic to aid students in their revision.
  • Excessive amounts of detail can make articles harder to read and less useful as a revision aid, so make sure the article is focused.
  • Articles should be written in full sentences and not simply as a list of bullet points. The aim is to create an article which is enjoyable to read.
  • UK spelling should be adopted for all articles.
  • Make sure to read our article style guide on bullet pointscapitalisation and general text styling as it’s important these remain consistent between articles.
  • Articles need to be referenced appropriately: see our article style guidelines for more details.
  • Any images used need to have an appropriate licence which allows re-use, see our article style guidelines for finding appropriately licenced images.
  • All articles should be reviewed by a senior wherever possible.

Useful resources

There are many great online resources which can be useful to use as research and write your article including:

It is important that you don’t simply copy and paste content from other sources. Instead, you should intelligently summarise the key points that are relevant to medical students.


Avoiding excessive detail

It is essential that you avoid including excessive amounts of detail in your article. Your article should provide a succinct overview which is ideal for final-year medical students wanting to quickly revise a specific topic. 


Introduction

Your article should begin with a brief explanation of the condition or topic that the article is covering. If the article is about a specific condition (e.g. ectopic pregnancy), you should begin by defining what the condition is. It may also be useful to include one or two key points about epidemiology (e.g. the prevalence, the incidence of condition) to help the reader gauge the topic’s practical relevance. Please include references, where appropriate.

Example

An ectopic pregnancy is one that occurs anywhere outside of the uterus. The most common location for ectopic pregnancy to occur is in one of the fallopian tubes. In the UK, there are approximately 11,000 ectopic pregnancies annually.1

Aetiology

This section should provide information on the underlying aetiology of the condition.

If warranted, you may need to include a focused sub-section on anatomy or pathophysiology of the condition, to ensure the aetiology is clearly explained. Avoid going into excessive detail and only include a brief overview that remains clinically relevant.

For example, it may be valuable to include an image and/or short description of the uterine anatomy, with associated sections of the fallopian tubes, to explain where and how ectopic pregnancy arises.


Risk factors

This section should cover the most important risk factors for the condition. Risk factors should be listed according to the descending order of prevalence where possible. Avoid trying to include every possible risk factor and instead focus on those which are most relevant.

Example

There is often no identifiable cause for ectopic pregnancy, however, the following risk factors are associated with an increased likelihood of developing the condition:

  • Assisted reproduction techniques (e.g. in-vitro fertilisation)
  • History of pelvic inflammatory disease (resulting in tubal occlusion due to adhesions)
  • Endometriosis

Clinical features

This section should provide a succinct summary of the condition’s typical clinical features. It can be broken down into:

  • History: a summary of the symptoms a patient may typically present with. Other important areas to cover in the history can also be included here if relevant (e.g. menstrual history). You can subtly link to our history guides if relevant (e.g. link the phrase menstrual history).
  • Clinical examination: a summary of the import clinical examinations that should be performed and the clinical signs associated with the condition. You can subtly link to our examinations guides if relevant (e.g. link the phrase cardiovascular exam).

Avoid trying to include every possible symptom or clinical sign associated with a condition and instead focus on those which are most common and relevant.

Example

History

Typical symptoms of ectopic pregnancy include:

  • Abdominal pain
  • Pelvic pain
  • Amenorrhoea or a missed period
  • Vaginal bleeding (with or without clots)
  • Dizziness, fainting or syncope
  • Shoulder tip pain
  • Breast tenderness
  • Dysuria
  • Passage of products of conception

Other important areas to cover in the history include:

  • Menstrual history (e.g. date of last menstrual period)
  • Sexual history (e.g. when did the patient last have unprotected sexual intercourse)
  • Medication history (e.g. contraceptives, anticoagulants)

Clinical examination

In the context of a suspected ectopic pregnancy, a thorough pelvic examination is necessary. 

Typical clinical findings in ectopic pregnancy include:

  • Pelvic or abdominal tenderness
  • Adnexal tenderness

Differential diagnoses

This section should briefly summarise what other diagnoses can present in a similar way to the primary condition and therefore should be considered.

There is often a wide range of potential differential diagnoses, but you should make sure to only include those felt to be most relevant.

Avoid including excessive information on the clinical features of the differential diagnoses as this can detract from the focus of the article.

Example

Possible differential diagnoses in the context of suspected ectopic pregnancy include:

  • Threatened miscarriage
  • Appendicitis
  • Pelvic inflammatory disease

Investigations

This section should provide a succinct summary of the important investigations that should be carried out if this condition is suspected.

You should break down this section into sub-sections based upon the type of investigation:

  • Bedside investigations (e.g. capillary blood glucose, ECG)
  • Laboratory investigations (e.g. blood tests, bacterial cultures)
  • Imaging (e.g. CT abdomen, echocardiogram)
  • Other investigations  (e.g. cardiac exercise stress test, risk scoring systems)

Provide some information beside each investigation, after a colon, about why the investigation is performed and if relevant, what the expected result might be (e.g. “Urinalysis: to rule out urinary tract infection”). You can include a second sentence if needed to provide further information (see urinalysis and serum hCG in the example below).

Again, make sure to keep this section focused.

Example

Bedside investigations

Relevant bedside investigations in the context of ectopic pregnancy include:

  • Urine pregnancy test (hCG urine dipstick): to rule pregnancy in or out. This investigation would be positive in the context of ectopic pregnancy.
  • Urinalysis: to rule out a urinary tract infection. If findings suggest a urinary tract infection, ectopic pregnancy would still need ruling out (as the patient may have both).

Laboratory investigations

Relevant laboratory investigations in the context of ectopic pregnancy include:

  • Baseline blood tests (FBC, U&E, Coagulation, CRP): white cells may be raised and there may be anaemia.
  • Serum hCG: the level will depend on the gestation and viability of the pregnancy. This is often used to monitor response to treatment (see below).
  • Group and save: important to perform as the patient may require a blood transfusion.

Imaging

Relevant imaging investigations in the context of ectopic pregnancy include:

  • Transvaginal ultrasound scan: the most accurate method of confirming the presence of tubal ectopic pregnancy.

Diagnosis

This section should be included if there are relevant diagnostic criteria which need to be met for a diagnosis to be made. If the diagnostic criteria are very brief (like in the example below) they may be included, but if they are more extensive, you should try to provide a brief summary and link to the criteria for students who want to learn more.

If diagnosis also involves the staging of the condition, this could also be briefly summarised, however, unless the staging information is extremely brief, it is more appropriate to link to the information.

Example

The below criteria must be met for a diagnosis of symptomatic myeloma:

  • Clonal plasma cells >10% on bone marrow biopsy or in a biopsy from other tissues
  • A monoclonal protein (paraprotein) in either serum or urine
  • Evidence of end-organ damage related to the plasma cell disorder

You can read more about the diagnostic criteria for myeloma here.


Management

This section needs to provide a brief overview of management options for the condition. It is very important that you avoid going too deep on the management specifics of the current guidelines whilst still providing the level of information a final year medical student would be expected to know for exams. The aim is to provide an easy to read overview of the general themes of management and then link to the official guidelines if students want to go deeper on the topic.

Example

Medical management

Systemic methotrexate is used as the first-line treatment for ectopic pregnancy. 

NICE recommends systemic methotrexate as the first-line option for women who meet the following criteria:

  • Able to return for follow-up
  • No significant pain
  • Unruptured ectopic pregnancy with an adnexal mass <35 mm and no visible heartbeat
  • No intrauterine pregnancy is seen on the ultrasound scan
  • Serum hCG <1500 IU/L

After administration of methotrexate, the patient’s serum hCG level will then need to be monitored to ensure it is declining. If serum hCG levels continue to rise, a further dose of systemic methotrexate may need to be administered.

Surgical management

Surgical management involves the surgical removal of the ectopic pregnancy.

Surgery should be offered to those women who meet any of the following criteria:

  • Unable to return for follow-up
  • Significant pain
  • Adnexal mass ≥35 mm
  • Fetal heartbeat visible on the scan
  • Serum hCG level ≥5000 IU/L

In cases of tubal ectopics, a laparoscopic salpingectomy is usually performed, removing both the ectopic pregnancy and the tube that it is implanted within.


Complications

This section needs to provide a brief summary of the potential complications of the condition. Again, include these in order of descending prevalence where possible. Avoid trying to include every possible complication and focus on those medical students would be expected to know.

Example

If an ectopic pregnancy is not diagnosed and treated promptly, complications can include:

  • Fallopian tube or uterine rupture
  • Secondary massive haemorrhage and disseminated intravascular coagulation
  • Death

Complications of surgical management can include:

  • Bleeding
  • Infection
  • Damage to local structures (bladder, bowel, vasculature)

Key points

The section needs to provide a summary of the important points a student should take away from the article. You should structure the key points as follows, using a maximum of two bullet points for each:

  • Definition
  • Aetiology/risk factors
  • Clinical features
  • Investigations/diagnosis
  • Management
  • Prognosis/complications

Example

Key points
  • An ectopic pregnancy is one that occurs anywhere outside of the uterus. [EXAMPLE OF DEFINITION]
  • The most common location for ectopic pregnancy to occur is in one of the fallopian tubes. [EXAMPLE OF AETIOLOGY/RISK FACTORS]
  • The most common symptoms include abdominal pain, pelvic pain, amenorrhoea and vaginal bleeding (with or without clots). [EXAMPLE OF CLINICAL FEATURES]
  • The most common clinical findings include pelvic or abdominal tenderness and adnexal tenderness. [EXAMPLE OF CLINICAL FEATURES]
  • Urine hCG, serum hCG and ultrasound abdomen are the primary investigations. [EXAMPLE OF INVESTIGATIONS/DIAGNOSIS]
  • Medical management involves the administration of systemic methotrexate, with ongoing monitoring of serum hCG levels. [EXAMPLE OF MANAGEMENT]
  • Surgical management involves the surgical removal of the ectopic pregnancy (most commonly a laparoscopic salpingectomy). [EXAMPLE OF MANAGEMENT]
  • Complications can include fallopian tube rupture, haemorrhage and death. [EXAMPLE OF PROGNOSIS/COMPLICATIONS]

References

See our article style guide for further details on how to structure references, including those for images.


Reviewer credits

At the bottom of your article, please cite the name and position of your senior reviewer. Also, indicate whether this person has given their approval to have their name published.

Example

Dr Hannah Smith, Consultant General Practitioner (is happy for their name to be published along with the article)