Knee Joint

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The knee joint is the largest joint in the body and connects the thigh with the lower leg. It is made up of two joints, the tibiofemoral joint (between the tibia and the femur), and the patellofemoral joint (between the patella and the femur).

The primary movements at the knee joint include flexion and extension, with limited internal and external rotation. The joint is stabilised by several of ligaments.

There are many muscles responsible for movement at the knee joint which, which are located in the thigh. These muscles are split into the anterior, medial and posterior compartments of the thigh and each compartment is responsible for a different movement at the knee joint.

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Bony structure

The knee joint is a compound joint, consisting of two different articulation points that combine to form the joint.

It may also be referred to as a bicondylar joint as movement primarily occurs in one plane (flexion, extension). The two articulations in the knee are found between the tibia and the femur (tibiofemoral) and the patella and the femur (patellofemoral).

Knee joint anatomy
Figure 1. Knee joint anatomy.3

Articular surfaces

The distal end of the femur and the proximal end of the tibia are both covered by a layer of hyaline cartilage, which allows the bones to slide over each other easily.Β 

The proximal end of the tibia is also covered by two menisci. Each meniscus is a C-shaped piece of fibrocartilage. There are two menisci found on the proximal tibia, the medial meniscus and the lateral meniscus whichΒ are connected by a series of ligaments that run through the joint capsule.

The function of the menisci is to assist the movement of the bones over each other, to deepen the tibial plateau and to act as a form of shock absorption.

Menisci of the knee joint
Figure 2. Menisci of the knee joint
Clinical relevance: Meniscal tears

Injury to the menisci can occur secondary to sudden twistingΒ of the knee (e.g. in football) which tears the meniscal tissue. Typically symptoms of meniscal injuries includeΒ sudden-onset pain, aΒ poppingΒ sensation,Β lockingΒ andΒ instabilityΒ of the knee joint.

Clinical relevance: Osteoarthritis of the knee

Osteoarthritis is a degenerative disease that primarily occurs in synovial joints. It involves degeneration of the articular surfaces. Symptoms of severe osteoarthritis include joint stiffness, reduced range of joint movement and joint pain.Β 

Typical X-ray findings of osteoarthritis include:

  • Joint space narrowingΒ 
  • Subchondral sclerosis: hardening of the bone beneath the joint surface
  • Osteophyte formation: small bony growths around the edges of the joint
  • Bony cyst formation

For more information, see the Geeky Medics guide to osteoarthritis.


Patellar ligament

The patellar ligament is a continuation of the quadriceps femoris tendon from the anterior compartment of the thigh. It runs over the patella, attaching around the margins of the bone, and inserts onto the tibial tuberosity.

Cruciate ligaments

Anterior cruciate ligament (ACL)

The ACL originates on the lateral condyle of the femur and inserts onto the anterior intercondylar area. Its function is to prevent anterior displacement of the knee. The ACL is the most commonly injured ligament of the knee.

Posterior cruciate ligament (PCL)

The PCL originates on the medial condyle of the femur and inserts onto the posterior intercondylar area. It prevents posterior displacement of the knee.

Cruciate ligaments of the knee
Figure 3. Cruciate ligaments of the knee joint

Collateral ligaments

Medial collateral ligament (MCL)

The MCL, also known as the tibial collateral ligament, runs from the medial epicondyle of the femur and inserts onto the medial condyle of the tibia. Its function is to stabilise the knee by preventing medial movement (maintaining the hinge-like properties of the joint). Without the MCL, the knee would have a valgus deformity. The MCL is also connected to the medial meniscus.

Lateral collateral ligament (LCL)

The LCL, or fibular collateral ligament, runs from the lateral epicondyle of the femur and inserts onto the head of the fibula. It is smaller in size compared to the MCL and is more flexible due to not being connected to any other structures within the knee joint. This flexibility makes the ligament less susceptible to injury. Its function is to prevent lateral movement of the knee joint and to prevent varus deformity.

Collateral ligaments of the knee joint
Figure 4. Collateral ligaments of the knee joint


The knee is surrounded by a series of bursae which act to reduce friction within the joint. Bursae are sacs filled with synovial fluid.

The largest bursae in the knee joint is the suprapatellar bursa, located above the patella between the femur and the quadriceps femoris muscle. The function of this bursa is to allow the quadriceps tendon to move freely over the femur. This is a communicating bursa, meaning it is attached to the synovial membrane of the joint capsule.

Other anterior knee bursae include the prepatellar bursa (between the patella and the skin) and the superficial and deep infrapatellar bursae (between the patellar ligament and the skin, and the patellar ligament and the tibia respectively).

There are also four smaller bursae located in the posterior knee which function to reduce friction between the joint capsule, ligaments and tendons of several muscles in the leg (gastrocnemius, biceps femoris, popliteus).

Ligaments and bursae of the knee joint
Figure 5. Ligaments and bursae of the knee joint.4

Blood supply and innervation

Blood supply of the knee joint

Blood supply to the knee originates from the femoral, popliteal and lateral circumflex femoral arteries. In combination with smaller arteries from the leg, they form an anastomotic network to supply the joint.

Arterial supply of the knee joint
Figure 6. Arterial supply of the knee joint

Innervation of the knee joint

Innervation of the joint involves branches of the obturator, femoral, tibial and common fibular nerves.


There are three groups of muscles that act to move the knee. These muscles originate from the anterior, posterior and medial compartments of the thigh.

Anterior compartment

The anterior compartment of the thigh acts to extend the knee joint. The compartment contains the quadriceps muscles. There are seven muscles located in this compartment, five of which act on the knee joint including:

  • Vastus medialis
  • Vastus intermedius
  • Vastus lateralis
  • Rectus femoris
  • Sartorius

The vastus muscles and rectus femoris join distally to form the quadriceps tendon which inserts onto the patella, stabilising it during movement.

Muscles of the anterior thigh
Figure 7. Muscles of the anterior thigh.4

Posterior compartment

The posterior compartment of the thigh contains three long muscles, collectively known as the hamstrings. These muscles are biceps femoris, semitendinosus, and semimembranosus.

The hamstrings contribute to flexion at the knee joint. As well as causing flexion, biceps femoris acts to externally rotate the knee when partly flexed. Semitendinosus and semimembranosus work together to internally rotate the knee.

For more information, see the Geeky Medics guide to the muscles of the posterior thigh.

Medial compartment

The medial compartment of the thigh contains six muscles, however only the gracilis muscle acts on the knee joint (the rest all act on the hip). This muscle causes flexion of the knee and runs from the ischiopubic ramus on the pelvis to the proximal tibia.

Figure 11. Gracilis

Table 1. Summary of the compartments of the thigh, including the muscles and relevant actions at the knee joint.



Action on the knee

Anterior (quadriceps)

Vastus medialis



Vastus intermedius


Vastus lateralis


Rectus femoris






Posterior (hamstrings)

Biceps femoris


External rotation



Internal rotation



  1. Drake, R. Gray’s Anatomy for Students (4th Edition). Feb 2019.
  2. Gray, Anatomy of the Human Body (1918).
  3. staff (2014). “Medical gallery of Blausen Medical 2014”. WikiJournal of Medicine 1 (2). DOI:10.15347/wjm/2014.010. ISSN 2002-4436. Licence: [CC BY]
  4. OpenStax. Anatomy and Physiology. April 2013. Available from: [LINK]


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