If you'd like to support us and get something great in return, check out our PDF OSCE Checklist Booklet containing over 100 OSCE checklists in PDF format.
Put your knowledge to the test with this thyroid pathology quiz.
Check out our brand new quiz platform, with over 2000 MCQs at geekyquiz.com
Thyroid pathology quiz
Question 1 |
A 28-year-old man presents to his GP with a 4cm mobile anterior neck mass. A fine needle aspirate is performed which reveals cells with ‘orphan Annie eye’ nuclei and psammoma bodies.
What is the most likely diagnosis?
Thyroglossal duct cyst | |
Follicular carcinoma | |
Medullary carcinoma | |
Papillary carcinoma | |
Lingual thyroid |
Question 2 |
Follicular carcinoma | |
Papillary carcinoma | |
Medullary carcinoma | |
Anaplastic carcinoma |
Question 3 |
Which of the following features is NOT typical for Graves disease?
Hyperplasia of the follicles | |
Scalloping of the colloid | |
Irregular shaped follicles | |
Infiltration of mononuclear cells into retro-orbital connective tissues | |
Extensive infiltration of the mononuclear cells into the thyroid parenchyma |
Question 4 |
A 37-year-old woman presents to the clinic with 2 days of sudden onset pain in the anterior neck radiating to the jaw. She is otherwise well having reported a full recovery from a ‘cold’ a week ago.
What findings are NOT consistent with her diagnosis?
Plasma cells aggregating around damaged thyroid follicles | |
Dense fibrosis of the thyroid gland | |
Neutrophilic infiltration of the thyroid | |
Formation of microabscesses | |
Multinucleated giant cells encapsulating colloid fragments |
Question 5 |
A 62-year-old gentleman presents to the clinic with a 5cm painless neck mass as well as diarrhoea for the past 3 months. A biopsy is taken and he is subsequently diagnosed with medullary carcinoma.
Which of the following features is consistent with a medullary carcinoma?
Grossly soft and tender mass | |
Diagnosis of MEN-1 syndrome | |
Haematologic metastatic spread | |
High levels of calcitonin | |
Localised amyloid deposits |
Question 6 |
Which of the following features is NOT consistent with follicular carcinoma?
Malignant proliferation of follicular cells | |
Follicular carcinomas are diagnosed via fine needle aspiration | |
More common in women than men | |
Commonly have PI-3K/AKT signalling pathway mutations | |
Uniform cells forming small colloid containing follicles |
Question 7 |
A 46-year-old female presents to the preadmission clinic and is found to have a 3cm anterolateral firm painless neck mass along with a minor decrease in calcium serum levels.
What is the most likely diagnosis?
Anaplastic carcinoma | |
Medullary carcinoma | |
Follicular carcinoma | |
Papillary carcinoma | |
Parathyroid carcinoma |
Question 8 |
Which of the following features are NOT consistent with anaplastic carcinoma?
Large, pleomorphic giant cells | |
Occasional osteoclast-like multinucleated giant cells | |
Spindle cells | |
Poor prognosis | |
Positive thyroglobulin markers |
Question 9 |
What thyroid cancer has the worst prognosis? (choose the answer that shows the correct descending order, the first being the cancer with the worst prognosis and the last being the one with the best prognosis)
anaplastic > medullary > follicular > papillary | |
anaplastic > medullary > papillary > follicular | |
anaplastic > papillary > medullary > follicular | |
medullary > anaplastic > papillary > follicular | |
medullary > anaplastic > follicular > papillary |
Question 10 |
An 18-year-old female presents with a painless 1cm mass in the anterior neck region. A biopsy is taken revealing fluid contained within pseudostratified columnar epithelium.
What is the most likely diagnosis?
Follicular adenoma | |
Branchial cyst | |
Thyroglossal duct cyst | |
Thyroid cystitis | |
Parotid tumour |