Mental State Examination (MSE) – OSCE Guide

The mental state examination (MSE) is a structured way of observing and describing a patient’s current state of mind, under the domains of appearance, attitude, behaviour, mood, affect, speech, thought process, thought content, perception, cognition and insight.

The purpose of the MSE is to obtain a comprehensive cross-sectional description of the patient’s mental state, which when combined with the biographical and historical information of the psychiatric history, allows the clinician to make an accurate diagnosis and formulation. Below is a framework that demonstrates the type of information that the mental state examination hopes to gain.

Check out the mental state examination mark scheme here.


The appearance of the patient may provide some clues as to their lifestyle and ability to self-care:

  • Distinctive features
  • Clothing
  • Posture/gait
  • Grooming/hygiene
  • Evidence of self-harm


A patient’s non-verbal communication may provide insights into their current mental state:

  • Eye contact
  • Facial expression
  • Psychomotor activity – motor activity related to mental processes (can be slowed or increased)
  • Body language / gestures / mannerisms
  • Level of arousal – calm / agitated / aggression
  • Ability to follow requests
  • Rapport / engagement


Rate of speech – pressured / slowed

Quantity of speech – minimal (e.g. only in response to questions) /excessive speech / complete absence of speech

Tone of speech  – monotonous / tremulous

Volume of speech – loud / quiet

Fluency and rhythm of speech – articulate / clear / slurred

Mood and Affect

Mood and affect both relate to emotion, however, they are not the same thing:

  • Affect represents an immediately expressed and observed emotion (e.g. the patient’s facial expression or overall demeanour)
  • Mood represents a sustained emotion present over a prolonged period of time that can alter an individual’s perception of the world
  • To understand the relationship between the two it can be useful to think of mood as the climate and affect as the weather
  • In the mental state exam affect is what you observe, whereas mood is what you enquire about as shown below


Mood refers to a sustained state of the patient’s inner feelings

To explore these you need to ask the patient questions about their mood:

  • “How are you feeling?”
  • “What is your current mood?”
  • “Have you been feeling low/depressed/anxious lately?”


Examples of various mood states:

  • Low/depressed
  • Anxious
  • Angry/irritable
  • Apathetic
  • Elated



Affect refers to an observable expression of a patient’s inner feelings.

You therefore should observe the patient’s facial expressions/demeanor to assess affect.

Quality of affect:

  • Sad/agitated/hostile
  • Euphoric/animated


Range of affect:

  • Restricted
  • Normal
  • Expansive


Intensity of affect:

  • Normal
  • Blunted
  • Flat


Fluctuations in affect:

  • Labile – easily changed between states


Thought form

Speed – accelerated / racing /  retarded

Flow/ coherence:

  • Linear – in a logical order
  • Incoherent – makes no logical sense
  • Circumstantial – lots of irrelevant/unnecessary details (not to the point)
  • Tangential – patient moves from one thought to the other that relate in some way but never gets to the point
  • Flight of ideas – there is an increased number of ideas, produced at a rapid pace
  • Perseveration – repetition of a particular response despite the absence/removal of the stimulus


Thought content

Abnormal beliefs/ delusions

Obsessions – patient is aware they are irrational, but obsessive thoughts continue to enter their head

Overvalued ideas – e.g. the perception of weight in a patient with anorexia nervosa

Suicidal thoughts

Homicidal/violent thoughts


Examples of questions to screen for thought content abnormalities:

  • “What’s been on your mind recently?”
  • “Are you worried about anything?”
  • “Do things seem unreal to you?”
  • “Are there any thoughts you have a hard time getting out of your head?”
  • “Do you think anyone is trying to harm you?”
  • “Do you have any beliefs that aren’t shared by others you know?”
  • “Do you ever think about ending your life?”
  • “Have you ever felt your life was not worth living?”
  • “Have you ever attempted to end your life?”
  • “Do you ever think about harming other people?”


Thought possession

Thought insertion – belief that thoughts can be put into the patient’s mind

Thought withdrawal – belief that thoughts can be removed from patient’s mind

Thought broadcasting – belief that others can hear the patient’s thoughts


Examples of questions to screen for thought possession abnormalities:

  • “Do you think people can put ideas in your head?”
  • “Have you ever felt like people have removed/erased things/memories from your mind?”
  • “Do you ever feel like others can hear what you’re thinking?


Hallucinations – a sensory perception without any external stimulation of the relevant sense that the patient believes IS real (e.g. hears voices but no sound present) 

Pseudo-hallucinations – the same as a hallucination but the patient is aware that it IS NOT real

Illusions – illusions are misinterpreted perception such as mistaking a shadow for a person (whereas a hallucination is a false perception)


Examples of questions to screen for perception abnormalities:

  • “Do you ever see, hear, smell, feel, or taste things that are not really there?”
  • “Did you think this was real at the time?”
  • “Do you still believe it was real?”


Basic testing:

  • Orientation (time/place/person)
  • Attention and concentration
  • Short-term memory

Detailed testing – Mini-mental state exam (MMSE/ACE-III)

Insight and Judgement


Is the patient able to recognise they have a problem or recognise what they’re experiencing is abnormal?

What does the patient think is the cause of the problem?

Does the patient want help with their problem?


Assess the patient’s general problem-solving ability

Example question:

  • “What would you do if you could smell smoke in your house?”

To complete the examination

Thank patient

Summarise findings


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