Musculoskeletal Pathology Quiz

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Put your knowledge of musculoskeletal pathology to the test with this quiz.


Musculoskeletal pathology quiz

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1 / 11

What is the pathogenesis of osteopetrosis (marble bone disease)?

2 / 11

Acute gout presents as painful inflammation of the big toe which is referred to as podagra. What is an acute treatment for gout?

3 / 11

A patient presents with a heliotrope rash, a malar rash and Gottron's papules on the elbows and knees. She cannot comb her hair or climb the stairs due to muscle weakness. Lab results show an increased creatine kinase,  positive antinuclear antibody (ANA) and anti-Jo-1 antibody. Biopsy reveals perimysial inflammation with perifascicular atrophy. She is treated with corticosteroids.

Which is the most likely diagnosis?

4 / 11

Select the cause(s) of vitamin D deficiency.

5 / 11

Which joint disease is associated with morning stiffness that improves with activity?

6 / 11

What are the key investigation findings in osteomalacia?

7 / 11

What bone tumour is associated with lifting of periosteum off bone producing the Codman triangle and a sunburst appearance on X-ray?

8 / 11

Synovial fluid was sampled for a joint condition and rhomboid shaped crystals with weak positive birefringence under polarised light were found.

Which joint disease do these findings indicate?

9 / 11

On biopsy, a mosaic pattern of lamellar bone is revealed. What disease is associated with these results?

10 / 11

Achondroplasia is a disorder of bone whereby there is a mutation in the fibroblast growth factor receptor 3 (FGFR3) gene leading to impaired cartilage proliferation in the growth plate.

Why is it that affected children have a normal sized head and vertebral column whilst arms and legs are shortened?

11 / 11

What bone disorder is caused by an autosomal dominant defect in the synthesis of collagen type 1?

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